Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 5/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4709660 | 0.89 | OPRM1 (0.41) | OPRM1ALOX5CYP1A2GAAPTGES | |
| SCHEMBL4708680 | 0.85 | S1PR4 (0.35) | OPRM1S1PR4S1PR5 | |
| SCHEMBL4708613 | 0.85 | OPRM1 (0.40) | OPRM1ALOX5CYP1A2GAAPTGES | |
| SCHEMBL4710095 | 0.84 | GCK (0.36) | OPRM1ALOX5CYP1A2GAAPTGES | |
| SCHEMBL4707356 | 0.79 | OPRM1 (0.41) | OPRM1CYP1A2GAALMNAHPGD | |
| SCHEMBL14343792 | 0.77 | OPRM1 (0.37) | OPRM1HPGDRECQLMEN1KMT2A | |
| SCHEMBL4706830 | 0.76 | OPRM1 (0.40) | OPRM1GAADRD2HPGDRECQL | |
| SCHEMBL4707718 | 0.75 | OPRM1 (0.40) | OPRM1CYP1A2GAALMNAHPGD | |
| SCHEMBL4707461 | 0.73 | S1PR4 (0.36) | OPRM1MEN1KMT2ASMN1; SMN2S1PR4 | |
| SCHEMBL4707023 | 0.72 | OPRM1 (0.39) | OPRM1GAALMNADRD2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879877-A2 | ANTIMICROBIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117762-A2 | ANTIMICROBIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |