Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 10/20 | 0.40 |
| ▸ | IDO1 | P14902 | 8/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL348838 | 0.81 | TDO2 (0.52) | TDO2IDO1NPC1RAB9ACASP3 | |
| SCHEMBL347960 | 0.79 | IDO1 (0.46) | TDO2IDO1NPC1RAB9ABRD4 | |
| SCHEMBL28288872 | 0.77 | TDO2 (0.53) | TDO2IDO1NPC1RAB9ACASP3 | |
| SCHEMBL348270 | 0.74 | SYK (0.51) | NPC1BRD4MEN1KMT2A | |
| SCHEMBL348727 | 0.72 | TDO2 (0.60) | TDO2IDO1NPC1RAB9ACASP3 | |
| SCHEMBL145706 | 0.71 | BRD4 (0.46) | BRD4HDAC1 | |
| SCHEMBL30434678 | 0.71 | BRD4 (0.46) | BRD4HDAC1 | |
| SCHEMBL28288947 | 0.70 | TDO2 (0.64) | TDO2IDO1NPC1RAB9ACASP3 | |
| SCHEMBL28290268 | 0.69 | TDO2 (0.65) | TDO2IDO1NPC1RAB9ACASP3 | |
| SCHEMBL22635791 | 0.69 | IDO1 (0.33) | TDO2IDO1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1909788-A2 | PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF COMPLEX DISEASES AND THEIR DELIVERY BY INSERTABLE MEDICAL DEVICES | RESVERLOGIX CORP. (CA) | 2008-04-16 | — | — | EP | claimed |
| WO-2007016525-A2 | PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF COMPLEX DISEASES AND THEIR DELIVERY BY INSERTABLE MEDICAL DEVICES | RESVERLOGIX CORP. (CA) | 2007-02-08 | — | — | WO | claimed |