Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11371607 | 1.00 | HDAC4 (0.55) | HDAC4HDAC2HDAC8HDAC6CHRM3 | |
| SCHEMBL14827239 | 1.00 | HDAC4 (0.55) | HDAC4HDAC2HDAC8HDAC6CHRM3 | |
| SCHEMBL15426906 | 1.00 | HDAC4 (0.55) | HDAC4HDAC2HDAC8HDAC6CHRM3 | |
| SCHEMBL11326897 | 1.00 | HDAC4 (0.55) | HDAC4HDAC2HDAC8HDAC6CHRM3 | |
| SCHEMBL9806702 | 1.00 | HDAC4 (0.55) | HDAC4HDAC2HDAC8HDAC6CHRM3 | |
| SCHEMBL11323894 | 1.00 | HDAC4 (0.55) | HDAC4HDAC2HDAC8HDAC6CHRM3 | |
| SCHEMBL15426911 | 1.00 | HDAC4 (0.55) | HDAC4HDAC2HDAC8HDAC6CHRM3 | |
| SCHEMBL9806700 | 1.00 | HDAC4 (0.55) | HDAC4HDAC2HDAC8HDAC6CHRM3 | |
| SCHEMBL11371613 | 1.00 | HDAC4 (0.55) | HDAC4HDAC2HDAC8HDAC6CHRM3 | |
| SCHEMBL809748 | 0.98 | HDAC2 (0.57) | HDAC4HDAC2HDAC8HDAC6CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4293717-A | Process for preparing aldehydes and diols | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-06 | — | — | US | claimed |
| CN-113135955-B | Novel optical pure Trost ligand and preparation method thereof | 西湖大学 | 2023-03-14 | — | — | CN | disclosed |
| CN-113336731-A | Flavaginess natural product asymmetric diversity guide synthesis method | 西湖大学 | 2021-09-03 | — | — | CN | disclosed |
| CN-113135955-A | Novel optical pure Trost ligand and preparation method thereof | 西湖大学 | 2021-07-20 | — | — | CN | disclosed |
| CN-105209448-B | Tricyclic compounds and uses thereof | 株式会社蒂奥姆生物 | 2018-09-14 | — | — | CN | disclosed |
| CN-108017603-A | Tricyclic compounds and uses thereof | 株式会社蒂奥姆生物 | 2018-05-11 | — | — | CN | disclosed |
| EP-0734854-B2 | Process for producing a polyolefin-based laminate film | TORAY INDUSTRIES (JP) | 2008-11-05 | — | — | EP | disclosed |
| EP-0734854-B1 | Polyolefin-based laminate film | TORAY INDUSTRIES (JP) | 2000-06-21 | — | — | EP | disclosed |
| US-5698317-A | MULTILAYER | TORAY INDUSTRIES, INC. (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0734854-A1 | Polyolefin-based laminate film | TORAY INDUSTRIES, INC. (JP) | 1996-10-02 | — | — | EP | disclosed |
| US-4293717-A | Process for preparing aldehydes and diols | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-06 | — | — | US | disclosed |
| US-3972944-A | BORON OXIDE, BORIC ACID OR BORATE AND VANADIUM OR MOLYBDENUM CONTAINING CATALYST | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-03 | — | — | US | disclosed |