Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11371607 | 1.00 | HDAC4 (0.55) | HDAC4HDAC2HDAC8HDAC6CHRM3 | |
| SCHEMBL15426906 | 1.00 | HDAC4 (0.55) | HDAC4HDAC2HDAC8HDAC6CHRM3 | |
| SCHEMBL11326897 | 1.00 | HDAC4 (0.55) | HDAC4HDAC2HDAC8HDAC6CHRM3 | |
| SCHEMBL9806702 | 1.00 | HDAC4 (0.55) | HDAC4HDAC2HDAC8HDAC6CHRM3 | |
| SCHEMBL4710137 | 1.00 | HDAC4 (0.55) | HDAC4HDAC2HDAC8HDAC6CHRM3 | |
| SCHEMBL11323894 | 1.00 | HDAC4 (0.55) | HDAC4HDAC2HDAC8HDAC6CHRM3 | |
| SCHEMBL15426911 | 1.00 | HDAC4 (0.55) | HDAC4HDAC2HDAC8HDAC6CHRM3 | |
| SCHEMBL9806700 | 1.00 | HDAC4 (0.55) | HDAC4HDAC2HDAC8HDAC6CHRM3 | |
| SCHEMBL11371613 | 1.00 | HDAC4 (0.55) | HDAC4HDAC2HDAC8HDAC6CHRM3 | |
| SCHEMBL809748 | 0.98 | HDAC2 (0.57) | HDAC4HDAC2HDAC8HDAC6CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120711-B2 | Carboxylation catalysts | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2015-09-01 | — | — | US | disclosed |
| US-20130085276-A1 | CARBOXYLATION CATALYSTS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2013-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130085276-A1 | CARBOXYLATION CATALYSTS | CTH, ME3, CPN1 | HDAC4 3808/4885HDAC2 3706/4885HDAC8 3132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.