Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 11/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4922607 | 0.95 | ALDH1A1 (0.49) | ALDH1A1HKDC1TSHRMEN1KMT2A | |
| SCHEMBL4925674 | 0.94 | ALDH1A1 (0.50) | ALDH1A1HKDC1TSHRMEN1KMT2A | |
| SCHEMBL4927782 | 0.73 | PDE4B (0.69) | PDE4BPDE4APDE4D | |
| SCHEMBL4924038 | 0.72 | PDE4B (0.78) | ALDH1A1MEN1KMT2APDE4BPDE4A | |
| SCHEMBL4708792 | 0.72 | PDE4B (0.78) | ALDH1A1TSHRMEN1KMT2APDE4B | |
| SCHEMBL4923387 | 0.71 | PDE4B (0.80) | PDE4BPDE4APDE4D | |
| SCHEMBL4924655 | 0.69 | PDE4B (0.80) | ALDH1A1MEN1KMT2APDE4BPDE4A | |
| SCHEMBL4711537 | 0.65 | ALDH1A1 (0.59) | ALDH1A1TSHRKMT2APOLBNPSR1 | |
| SCHEMBL4914577 | 0.64 | PDE4B (0.83) | ALDH1A1TSHRMEN1KMT2APDE4B | |
| SCHEMBL4914020 | 0.63 | ALDH1A1 (0.58) | ALDH1A1HKDC1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1913003-A1 | NEW PYRIDO[3',2':4,5]FURO[3,2-d]PYRIMIDINE DERIVATIVES | Laboratorios Almirall, S.A. (ES) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007017078-A1 | NEW PYRIDO[3',2':4,5]FURO[3,2-d]PYRIMIDINE DERIVATIVES | LABORATORIOS ALMIRALL, S.A. (ES) | 2007-02-15 | — | — | WO | disclosed |