SCHEMBL4710902

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7811164	0.89	KMT2A (0.36)	ALDH1A1GAAPBRM1NQO2KMT2A
	SCHEMBL28782471	0.81	KMT2A (0.45)	ALDH1A1CYP3A4PDE4APDE4BPDE4C
	SCHEMBL3628529	0.79	EPAS1 (0.41)	ALDH1A1CYP1A1CYP1B1
	SCHEMBL4713706	0.77	ALDH1A1 (0.48)	ALDH1A1GAACYP1A1CYP1B1CYP1A2
	SCHEMBL4716539	0.75	ALDH1A1 (0.46)	ALDH1A1GAACYP1A1CYP1B1CYP1A2
	SCHEMBL11854342	0.75	ALDH1A1 (0.46)	ALDH1A1GAACYP1A1CYP1B1CYP3A4
	SCHEMBL28360321	0.75	ALDH1A1 (0.58)	ALDH1A1CYP1A1CYP1B1CYP1A2CYP2E1
	SCHEMBL24094553	0.74	KDM4E (0.39)	ALDH1A1GAACYP1A1CYP1B1PDE4A
	SCHEMBL30340528	0.74	KDM4E (0.39)	ALDH1A1GAACYP1A1CYP1B1PDE4A
	SCHEMBL9493364	0.73	ALDH1A1 (0.44)	ALDH1A1GAACYP1A1CYP1B1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.