SCHEMBL4711341

SCHEMBL4711341

CC(=C(C)c1ccccc1C)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
HPGD P15428 1/20 0.42
KCNK3 O14649 1/20 0.42
KCNK9 Q9NPC2 1/20 0.42
ESR1 P03372 1/20 0.42
ERCC5 P28715 1/20 0.41
FEN1 P39748 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
ALDH1A1 P00352 1/20 0.41
KMT2A Q03164 1/20 0.40
TSHR P16473 1/20 0.39
ACHE P22303 1/20 0.39
MYC P01106 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4318500 0.85 KMT2A (0.42) NPC1RAB9AHPGDKCNK3KCNK9
SCHEMBL19904128 0.84 KMT2A (0.49) NPC1RAB9AHPGDSMN1; SMN2KMT2A
SCHEMBL16329878 0.81 HPGD (0.45) HPGDERCC5FEN1SMN1; SMN2ALDH1A1
SCHEMBL21515796 0.81 RAB9A (0.47) NPC1RAB9AHPGDKCNK3KCNK9
SCHEMBL3902058 0.80 ESR1 (0.56) ESR1ALDH1A1TSHR
SCHEMBL1035354 0.80 ESR1 (0.56) ESR1ALDH1A1TSHR
SCHEMBL11844374 0.80 ESR1 (0.56) ESR1ALDH1A1TSHR
SCHEMBL3461999 0.79 NPC1 (0.44) NPC1RAB9AHPGDKCNK3KCNK9
SCHEMBL9248001 0.78 TSHR (0.45) HPGDERCC5FEN1SMN1; SMN2ALDH1A1
SCHEMBL23278527 0.77 ESR1 (0.61) ESR1SMN1; SMN2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1570014-B1 POLYSILAZANE-CONTAINING COATING SOLUTION AZ ELECTRONIC MATERIALS USA (US) 2013-03-13 EP disclosed
CN-101810600-B Methods and compositions for prevention and treatment of inflammatory disease, autoimmune disease, and transplant rejection UNIV CALIFORNIA 2012-11-21 CN disclosed
CN-101810600-A Methods and compositions for prevention and treatment of inflammatory disease, autoimmune disease, and transplant rejection UNIV CALIFORNIA 2010-08-25 CN disclosed
CN-100586428-C Composition for preventing and treating inflammatory diseases, autoimmune diseases, and transplant rejection, and pharmaceutical use thereof UNIV CALIFORNIA 2010-02-03 CN disclosed
EP-1398359-B1 ANTI-STAINING COATING SOLUTION COMPRISING INORGANIC POLYSILAZANE CLARIANT FINANCE BVI LTD (VG) 2008-09-17 EP disclosed
CN-1729007-A Compositions and methods for preventing and treating inflammatory diseases, autoimmune diseases, and transplant rejection UNIV CALIFORNIA (US) 2006-02-01 CN disclosed
US-20050279255-A1 Polysilane-containing coating solution CLARIANT INTERNATIONAL LTD. (CH) 2005-12-22 US disclosed
EP-1570014-A1 POLYSILAZANE-CONTAINING COATING SOLUTION CLARIANT INTERNATIONAL LTD. (CH) 2005-09-07 EP disclosed
US-6780913-B2 DISPERSES IN A RESIN, MARKEDLY IMPROVES SMOOTHNESS, LUSTER AND APPEARANCE OF THE SURFACES OF RESIN BLENDED THEREWITH, AND ELECTRIC PROPERTIES OF THE RESIN, AS FLAME-RETARDING AGENT OR A SMOKE-SUPPRESSING AGENT MIZUSAWA INDUSTRIAL CHEMICALS, LTD. (JP) 2004-08-24 US disclosed
WO-2004039904-A1 POLYSILAZANE-CONTAINING COATING SOLUTION CLARIANT INTERNATIONAL LTD (CH) 2004-05-13 WO disclosed
EP-1398359-A1 ANTI-STAINING COATING SOLUTION COMPRISING INORGANIC POLYSILAZANE CLARIANT INTERNATIONAL LTD. (CH) 2004-03-17 EP disclosed
US-20030164113-A1 Anti-staining coating solution comprising inorganic polysilazane CLARIANT FINANCE (BVI) LIMITED (VG) 2003-09-04 US disclosed
US-20030030042-A1 Zinc borate, and production method and use thereof MIZUSAWA INDUSTRIAL CHEMICALS, LTD. (JP) 2003-02-13 US disclosed
EP-1205439-A1 ZINC BORATE, AND PRODUCTION METHOD AND USE THEREOF Mizusawa Industrial Chemicals Ltd. (JP) 2002-05-15 EP disclosed