Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5650003 | 0.73 | GBA1 (0.45) | SLC6A3SLC6A4SLC6A2HTR1AMEN1 | |
| SCHEMBL5651523 | 0.68 | SLC6A2 (0.50) | SLC6A3SLC6A4SLC6A2HTR1AMEN1 | |
| SCHEMBL5808125 | 0.67 | CYP2D6 (0.43) | HTR1ASOS1MEN1LMNACYP2D6 | |
| SCHEMBL1506033 | 0.65 | SOS1 (0.43) | SLC6A3SLC6A4SLC6A2HTR1ASOS1 | |
| SCHEMBL14962097 | 0.65 | SLC6A2 (0.59) | SLC6A3SLC6A4SLC6A2HTR1A | |
| SCHEMBL21382026 | 0.65 | OPRD1 (0.53) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7325604 | 0.65 | OPRD1 (0.53) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL21382056 | 0.65 | OPRD1 (0.53) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL30149800 | 0.65 | OPRD1 (0.53) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7446561 | 0.64 | HTR2C (0.41) | SLC6A3SLC6A4SLC6A2HTR1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1734948-A4 | TRI-SUBSTITUED 2-BENZHYDRYL-5-BENZLAMINO-TETRAHYDRO-PYRAN-4-OL AND 6-BENZHYDRYL-4-BENZYLAMINO-TETRAHYDRO-PYRAN-3-OL ANALOGUES, AND NOVEL 3,6-DISUBSTITUTED PYRAN DERIVATIVES | UNIV WAYNE STATE (US) | 2008-04-16 | — | — | EP | disclosed |
| EP-1734948-A1 | TRI-SUBSTITUED 2-BENZHYDRYL-5-BENZLAMINO-TETRAHYDRO-PYRAN-4-OL AND 6-BENZHYDRYL-4-BENZYLAMINO-TETRAHYDRO-PYRAN-3-OL ANALOGUES, AND NOVEL 3,6-DISUBSTITUTED PYRAN DERIVATIVES | WAYNE STATE UNIVERSITY (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005105075-A1 | TRI-SUBSTITUED 2-BENZHYDRYL-5-BENZLAMINO-TETRAHYDRO-PYRAN-4-OL AND 6-BENZHYDRYL-4-BENZYLAMINO-TETRAHYDRO-PYRAN-3-OL ANALOGUES, AND NOVEL 3,6-DISUBSTITUTED PYRAN DERIVATIVES | WAYNE STATE UNIVERSITY (US) | 2005-11-10 | — | — | WO | disclosed |