SCHEMBL471154

CCCCN(c1nc(NCCCNc2nc(N(CCCC)C3CC(C)(C)N(C)C(C)(C)C3)nc(N(CCCC)C3CC(C)(C)N(C)C(C)(C)C3)n2)nc(N(CCCC)C2CC(C)(C)N(C)C(C)(C)C2)n1)C1CC(C)(C)N(C)C(C)(C)C1

nearest known ligand 0.37

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	FLT3	P36888	1/20	0.37

▸	TYRO3	Q06418	1/20	0.37

▸	MERTK	Q12866	1/20	0.37

▸	GAS6	Q14393	1/20	0.37

▸	SMN1; SMN2	Q16637	2/20	0.32

▸	HRH4	Q9H3N8	1/20	0.30

▸	DNM2	P50570	6/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL13531453	0.98	FLT3 (0.39)	FLT3TYRO3MERTKGAS6SMN1; SMN2
SCHEMBL9373111	0.96	FLT3 (0.38)	FLT3TYRO3MERTKGAS6SMN1; SMN2
SCHEMBL13415273	0.95	FLT3 (0.38)	FLT3TYRO3MERTKGAS6DNM2
SCHEMBL13415270	0.95	FLT3 (0.38)	FLT3TYRO3MERTKGAS6DNM2
SCHEMBL13415266	0.95	FLT3 (0.38)	FLT3TYRO3MERTKGAS6DNM2
SCHEMBL10167129	0.94	FLT3 (0.35)	FLT3TYRO3MERTKGAS6SMN1; SMN2
SCHEMBL10135487	0.93	FLT3 (0.35)	FLT3TYRO3MERTKGAS6
SCHEMBL10135472	0.93	FLT3 (0.35)	FLT3TYRO3MERTKGAS6
SCHEMBL10135486	0.93	FLT3 (0.35)	FLT3TYRO3MERTKGAS6
SCHEMBL13415274	0.93	FLT3 (0.38)	FLT3TYRO3MERTKGAS6DNM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2240542-B9	LOW-STICKY ADDITIVE PACKAGE FOR AUTOMOTIVE INTERIOR APPLICATIONS	BOREALIS AG (AT)	2012-01-11	—	—	EP	disclosed