Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | SELL | P14151 | 1/20 | 0.39 |
| ▸ | SELP | P16109 | 1/20 | 0.39 |
| ▸ | SELE | P16581 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29216775 | 0.88 | SELL (0.43) | ALDH1A1KDM4EMAPTLMNAGAA | |
| SCHEMBL20777579 | 0.78 | KDM4E (0.40) | ALDH1A1KDM4EMAPTLMNAGAA | |
| SCHEMBL19779546 | 0.78 | PTGS1 (0.42) | KDM4ECA2CA1TSHRTTR | |
| SCHEMBL22824216 | 0.78 | TTR (0.48) | ALDH1A1TDP1POLBKMT2ACA2 | |
| SCHEMBL13855817 | 0.78 | SELL (0.41) | ALDH1A1SELLSELPSELETTR | |
| SCHEMBL31287357 | 0.78 | TTR (0.39) | ALDH1A1KDM4EMAPTLMNAGAA | |
| SCHEMBL1852238 | 0.78 | TTR (0.39) | ALDH1A1KDM4EMAPTLMNAGAA | |
| Water SCHEMBL28440240 | 0.77 | ALDH1A1 (0.62) | ALDH1A1KDM4EMAPTLMNAGAA | |
| SCHEMBL10873192 | 0.76 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTTDP1POLB | |
| SCHEMBL13854373 | 0.75 | SMN1; SMN2 (0.63) | ALDH1A1KDM4EMAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2584901-A1 | A PROCESS FOR ETRA VIRINE INTERMEDIATE AND POLYMORPHS OF ETRAVIRINE | Hetero Research Foundation (IN) | 2013-05-01 | — | — | EP | disclosed |
| WO-2012001695-A1 | A PROCESS FOR ETRA VIRINE INTERMEDIATE AND POLYMORPHS OF ETRAVIRINE | HETERO RESEARCH FOUNDATION (IN) | 2012-01-05 | — | — | WO | disclosed |
| EP-2381308-A2 | Positive-working photosensitive resin composition, method for producing pattern-formed resin film, semiconductor device, display device, and method for producing the semiconductor device and the display device | SUMITOMO BAKELITE CO., LTD. (JP) | 2011-10-26 | — | — | EP | disclosed |
| EP-1909788-A2 | PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF COMPLEX DISEASES AND THEIR DELIVERY BY INSERTABLE MEDICAL DEVICES | RESVERLOGIX CORP. (CA) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007016525-A2 | PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF COMPLEX DISEASES AND THEIR DELIVERY BY INSERTABLE MEDICAL DEVICES | RESVERLOGIX CORP. (CA) | 2007-02-08 | — | — | WO | disclosed |