Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 18/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052045 | 0.93 | ADORA2B (0.66) | ADORA2BADORA1ADORA3ADORA2A | |
| SCHEMBL4054039 | 0.92 | ADORA2B (0.64) | ADORA2BADORA1ADORA3ADORA2A | |
| SCHEMBL4050484 | 0.90 | ADORA2B (0.63) | ADORA2BADORA1ADORA3ADORA2A | |
| SCHEMBL4053029 | 0.90 | ADORA2B (0.58) | ADORA2BADORA1ADORA3ADORA2A | |
| SCHEMBL4055594 | 0.87 | ADORA2B (0.64) | ADORA2BADORA1ADORA3ADORA2A | |
| SCHEMBL4053939 | 0.85 | ADORA2B (0.56) | ADORA2BADORA1ADORA3ADORA2A | |
| SCHEMBL4051673 | 0.85 | ADORA2B (0.73) | ADORA2BADORA1ADORA3ADORA2A | |
| SCHEMBL4051040 | 0.84 | ADORA2B (0.63) | ADORA2BADORA1ADORA3ADORA2A | |
| SCHEMBL4055021 | 0.84 | ADORA2B (0.73) | ADORA2BADORA1ADORA3ADORA2A | |
| SCHEMBL4716534 | 0.84 | ADORA2B (0.51) | ADORA2BADORA1ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492793-B1 | NEW-4-(PYRROLOPYRIMIDIN-6-YL)BENZENESULPHONAMIDE DERIVATIVES | ALMIRALL LAB (ES) | 2008-01-16 | — | — | EP | disclosed |