Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.61 |
| ▸ | BCR | P11274 | 3/20 | 0.61 |
| ▸ | PRKCA | P17252 | 2/20 | 0.61 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.58 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.58 |
| ▸ | SRC | P12931 | 2/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | SYK | P43405 | 1/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4895454 | 0.87 | ABL1 (0.80) | ABL1BCRPRKCAMAPK8PIK3CG | |
| SCHEMBL4903688 | 0.86 | MAPK8 (0.63) | ABL1BCRPRKCAMAPK8PIK3CG | |
| Hydrochloric Acid SCHEMBL27711429 | 0.86 | ABL1 (0.79) | ABL1BCRPRKCAMAPK8PIK3CG | |
| SCHEMBL4903516 | 0.85 | MAPK8 (0.68) | ABL1BCRPRKCAMAPK8PIK3CG | |
| Hydrochloric Acid SCHEMBL27708725 | 0.85 | ABL1 (0.77) | ABL1BCRPRKCAMAPK8PIK3CG | |
| SCHEMBL3747896 | 0.84 | CAMKK2 (0.80) | ABL1BCRPRKCAMAPK8PIK3CG | |
| SCHEMBL3758823 | 0.81 | MAPK8 (0.76) | ABL1BCRPRKCAMAPK8PIK3CG | |
| SCHEMBL5039680 | 0.81 | AURKA (0.62) | AURKASYK | |
| SCHEMBL4710600 | 0.80 | SYK (0.66) | MAPK8PIK3CGGSK3BCAMKK2SRC | |
| SCHEMBL29818161 | 0.80 | ROCK1 (0.50) | ABL1BCRPRKCAMAPK8PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1922309-A1 | N-PHENYL-2-PYRIMIDINE-AMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Il Yang Pharm. Co. Ltd. (KR) | 2008-05-21 | — | — | EP | disclosed |
| WO-2007018325-A1 | N-PHENYL-2-PYRIMIDINE-AMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | IL-YANG PHARM. CO., LTD. (KR) | 2007-02-15 | — | — | WO | disclosed |