SCHEMBL4712503

SCHEMBL4712503

Nc1ccc(N2CCCC(NC(=O)O)C2=O)cc1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 20/20 0.49
FPR1 P21462 13/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3495094 0.88 FPR2 (0.54) FPR2FPR1
SCHEMBL18955168 0.87 FPR2 (0.57) FPR2FPR1
SCHEMBL18955171 0.87 FPR2 (0.57) FPR2FPR1
SCHEMBL22179868 0.83 FPR2 (0.67) FPR2FPR1
SCHEMBL5637427 0.83 FPR2 (0.54) FPR2FPR1
SCHEMBL22159417 0.82 FPR2 (0.48) FPR2FPR1
SCHEMBL20581303 0.82 FPR2 (0.48) FPR2FPR1
SCHEMBL14022306 0.81 FPR2 (0.45) FPR2FPR1
SCHEMBL20581992 0.81 FPR2 (0.50) FPR2FPR1
SCHEMBL20581845 0.80 FPR2 (0.48) FPR2FPR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1824844-B1 PYRAZINE DICARBOXAMIDES AND THE USE THEREOF BAYER HEALTHCARE AG (DE) 2008-11-05 EP disclosed
EP-1824844-A1 PYRAZINE DICARBOXAMIDES AND THE USE THEREOF Bayer HealthCare AG (DE) 2007-08-29 EP disclosed
WO-2006061116-A1 PYRAZINE DICARBOXAMIDES AND THE USE THEREOF BAYER HEALTHCARE AG (DE) 2006-06-15 WO disclosed