Ditiocarb

Ditiocarb

SCHEMBL4713616

CCN(CC)C(=S)S.CCN(CC)CC

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB11 O95342 2/20 0.83
HTT P42858 2/20 0.83
GSDMD P57764 2/20 0.83
CYP2E1 P05181 1/20 0.83
PTGS1 P23219 1/20 0.83
ALDH1A1 P00352 5/20 0.46
CYP2C9 P11712 2/20 0.46
HPGD P15428 2/20 0.46
HSD17B10 Q99714 2/20 0.46
CA12 O43570 4/20 0.43
CA1 P00915 4/20 0.43
CA2 P00918 4/20 0.43
CA9 Q16790 4/20 0.43
EHMT2 Q96KQ7 3/20 0.43
EHMT1 Q9H9B1 3/20 0.43
CA4 P22748 2/20 0.43
MGLL Q99685 4/20 0.42
PHGDH O43175 3/20 0.42
ALDH2 P05091 3/20 0.42
CYP3A4 P08684 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ditiocarb SCHEMBL48382 0.91
Ditiocarb SCHEMBL7898491 0.88
Ditiocarb SCHEMBL81092 0.88 ABCB11 (0.94) ABCB11HTTGSDMDCYP2E1PTGS1
Ditiocarb SCHEMBL1395953 0.88 ABCB11 (0.94) ABCB11HTTGSDMDCYP2E1PTGS1
Ditiocarb SCHEMBL23045104 0.88
Ditiocarb SCHEMBL25284941 0.88 ABCB11 (0.94) ABCB11HTTGSDMDCYP2E1PTGS1
Ditiocarb SCHEMBL16735397 0.88
Ditiocarb SCHEMBL2236180 0.88
Ditiocarb SCHEMBL21359739 0.88 ABCB11 (0.94) ABCB11HTTGSDMDCYP2E1PTGS1
Ditiocarb SCHEMBL21801890 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1888060-A2 NK-B INHIBITORS FOR THE TREATMENT OF MUSCULAR DYSTROPHY A. T. Still University of Health Sciences (US) 2008-02-20 EP claimed
WO-2006127930-A2 NK-B INHIBITORS FOR THE TREATMENT OF MUSCULAR DYSTROPHY A. T. STILL UNIVERSITY OF HEALTH SCIENCES (US) 2006-11-30 WO claimed
CN-112912191-B Composition comprising silver nanoplatelets 巴斯夫欧洲公司 2023-11-21 CN disclosed
US-9302274-B2 Collector compositions and methods of using the same CYTEC TECHNOLOGY CORP. (US) 2016-04-05 US disclosed
US-9302272-B2 Froth flotation processes CYTEC TECHNOLOGY CORP. (US) 2016-04-05 US disclosed
EP-2768618-A2 FROTH FLOTATION PROCESSES Cytec Technology Corp. (US) 2014-08-27 EP disclosed
EP-2768616-A2 COLLECTOR COMPOSITIONS AND METHODS OF USING THE SAME Cytec Technology Corp. (US) 2014-08-27 EP disclosed
WO-2013059258-A2 COLLECTOR COMPOSITIONS AND METHODS OF USING THE SAME CYTEC TECHNOLOGY CORP. (US) 2013-04-25 WO disclosed
WO-2013059259-A2 FROTH FLOTATION PROCESSES CYTEC TECHNOLOGY CORP. (US) 2013-04-25 WO disclosed
US-20130092604-A1 Froth Flotation Processes CYTEC TECHNOLOGY CORP. (US) 2013-04-18 US disclosed
US-20130092603-A1 Collector Compositions and Methods of Using the Same CYTEC TECHNOLOGY CORP. (US) 2013-04-18 US disclosed