Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | HPGD | P15428 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 4/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyric Acid SCHEMBL4160930 | 0.92 | RXFP1 (0.38) | RXFP1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL4717999 | 0.90 | RXFP1 (0.43) | RXFP1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL3248746 | 0.82 | KDM4E (0.41) | RXFP1ALDH1A1HPGDKDM4EHSD17B10 | |
| Butyric Acid SCHEMBL4158045 | 0.82 | RXFP1 (0.39) | RXFP1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL4717113 | 0.81 | RXFP1 (0.36) | RXFP1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL4716505 | 0.81 | RXFP1 (0.38) | RXFP1ALDH1A1HPGDKDM4EHSD17B10 | |
| Butyric Acid SCHEMBL4162647 | 0.80 | RXFP1 (0.42) | RXFP1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL13928183 | 0.78 | HPGD (0.41) | RXFP1ALDH1A1HPGDKDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL4160925 | 0.78 | HPGD (0.36) | RXFP1ALDH1A1HPGDKDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL3253818 | 0.77 | HPGD (0.40) | RXFP1ALDH1A1HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899335-A1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PIERRE FABRE MEDICAMENT (FR) | 2008-03-19 | — | — | EP | claimed |
| WO-2007003611-A1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PIERRE FABRE MEDICAMENT (FR) | 2007-01-11 | — | — | WO | claimed |