Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 9/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | TEC | P42680 | 1/20 | 0.36 |
| ▸ | TXK | P42681 | 1/20 | 0.36 |
| ▸ | BMX | P51813 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 4/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7554372 | 0.91 | KDM4D (0.38) | BTKCTSKPIM1PIM3PIM2 | |
| SCHEMBL7514351 | 0.88 | KDM4D (0.35) | BTKCTSKPIM1PIM3PIM2 | |
| SCHEMBL7516546 | 0.88 | BTK (0.39) | BTKCTSKPIM1PIM3PIM2 | |
| SCHEMBL4515657 | 0.88 | BTK (0.40) | BTKCTSKPIM1PIM3PIM2 | |
| SCHEMBL7511874 | 0.86 | SUV39H2 (0.38) | BTKCTSKPIM1PIM3PIM2 | |
| SCHEMBL4506885 | 0.85 | BTK (0.39) | BTKCTSKPIM1PIM3PIM2 | |
| SCHEMBL7510364 | 0.85 | SUV39H2 (0.40) | KDM4D | |
| SCHEMBL4514369 | 0.84 | BTK (0.38) | BTKCTSKPIM1PIM3PIM2 | |
| SCHEMBL7508482 | 0.84 | BTK (0.38) | BTKCTSKJAK3KDM4DTRPV1 | |
| SCHEMBL28750386 | 0.82 | BTK (0.39) | BTKCTSKPIM1PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255739-B1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER LAMBERT CO (US) | 2008-06-11 | — | — | EP | disclosed |
| EP-1255739-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001053273-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2001-07-26 | — | — | WO | disclosed |