Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1382207 | 0.95 | KCNH2 (0.40) | KCNH2SCN5ATOP1 | |
| Hydrochloric Acid SCHEMBL4501179 | 0.94 | KCNH2 (0.40) | KCNH2SCN5ATOP1 | |
| SCHEMBL1382223 | 0.87 | KCNH2 (0.42) | KCNH2SCN5A | |
| Hydrochloric Acid SCHEMBL4516003 | 0.86 | KCNH2 (0.41) | KCNH2SCN5A | |
| SCHEMBL4521087 | 0.84 | CCR5 (0.36) | KCNH2SCN5A | |
| SCHEMBL1382693 | 0.82 | KCNH2 (0.42) | KCNH2SCN5A | |
| Hydrochloric Acid SCHEMBL4515749 | 0.81 | KCNH2 (0.41) | KCNH2SCN5A | |
| SCHEMBL1383803 | 0.81 | KCNH2 (0.45) | KCNH2SCN5A | |
| SCHEMBL6491008 | 0.80 | KCNH2 (0.44) | KCNH2SCN5A | |
| Hydrochloric Acid SCHEMBL4519316 | 0.80 | KCNH2 (0.45) | KCNH2SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255739-B1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER LAMBERT CO (US) | 2008-06-11 | — | — | EP | claimed |