Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.52 |
| ▸ | CTSS | P25774 | 15/20 | 0.52 |
| ▸ | CTSL | P07711 | 12/20 | 0.47 |
| ▸ | CTSB | P07858 | 8/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4714222 | 0.92 | CTSK (0.49) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4713187 | 0.84 | CTSK (0.73) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4716709 | 0.82 | CTSK (0.57) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4716585 | 0.81 | CTSK (0.54) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6218439 | 0.77 | CTSK (0.55) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4712345 | 0.77 | CTSK (0.70) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4712624 | 0.76 | CTSK (0.51) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6217523 | 0.76 | CTSK (0.56) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6216758 | 0.75 | CTSK (0.47) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6218094 | 0.71 | CTSK (0.48) | CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1248612-B1 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | MERCK FROSST CANADA LTD (CA) | 2008-02-27 | — | — | EP | disclosed |
| US-6525036-B2 | Treating post-menopausal osteoporosis. | MERCK & CO., INC. | 2003-02-25 | — | — | US | disclosed |