Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 20/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 19/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 16/20 | 0.74 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL471589 | 0.89 | OPRD1 (0.93) | OPRD1KCNH2CYP2D6OPRM1OPRK1 | |
| Adl-5747 Free Base SCHEMBL471356 | 0.85 | OPRD1 (1.00) | OPRD1KCNH2CYP2D6OPRM1OPRK1 | |
| SCHEMBL16315375 | 0.84 | OPRD1 (0.56) | OPRD1KCNH2CYP2D6OPRM1OPRK1 | |
| SCHEMBL471638 | 0.80 | OPRD1 (0.89) | OPRD1KCNH2CYP2D6OPRM1OPRK1 | |
| SCHEMBL467315 | 0.79 | OPRD1 (1.00) | OPRD1KCNH2CYP2D6OPRM1OPRK1 | |
| SCHEMBL471448 | 0.79 | OPRD1 (1.00) | OPRD1KCNH2CYP2D6OPRM1OPRK1 | |
| SCHEMBL471512 | 0.78 | OPRD1 (0.73) | OPRD1KCNH2CYP2D6OPRM1OPRK1 | |
| SCHEMBL12265419 | 0.77 | OPRD1 (0.68) | OPRD1KCNH2CYP2D6OPRM1OPRK1 | |
| SCHEMBL471412 | 0.77 | OPRD1 (1.00) | OPRD1KCNH2CYP2D6OPRM1OPRK1 | |
| SCHEMBL10258888 | 0.76 | OPRD1 (1.00) | OPRD1KCNH2CYP2D6OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033299-A2 | USE OF N-CONTAINING SPIROCOMPOUNDS FOR THE ENHANCEMENT OF COGNITIVE FUNCTION | ADOLOR CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |