Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6717087 | 0.82 | TSHR (0.43) | KMT2ASMN1; SMN2HTTMEN1TSHR | |
| SCHEMBL4017087 | 0.81 | KMT2A (0.51) | KMT2ASMN1; SMN2HTTMEN1TSHR | |
| SCHEMBL1852234 | 0.79 | HTT (0.51) | KMT2ASMN1; SMN2HTTMEN1TSHR | |
| SCHEMBL1853562 | 0.78 | KMT2A (0.50) | KMT2ASMN1; SMN2HTTMEN1TSHR | |
| SCHEMBL1855562 | 0.76 | TSHR (0.41) | KMT2ASMN1; SMN2HTTMEN1TSHR | |
| SCHEMBL4715548 | 0.76 | MAPT (0.37) | KMT2ASMN1; SMN2HTTMEN1TSHR | |
| SCHEMBL4715407 | 0.75 | SMN1; SMN2 (0.69) | KMT2ASMN1; SMN2HTTMEN1TSHR | |
| SCHEMBL4019374 | 0.74 | MEN1 (0.47) | KMT2ASMN1; SMN2HTTMEN1TSHR | |
| SCHEMBL5047436 | 0.74 | MAPT (0.36) | KMT2ASMN1; SMN2HTTMEN1TSHR | |
| SCHEMBL4019801 | 0.74 | MEN1 (0.47) | KMT2ASMN1; SMN2HTTMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986637-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | Laboratoires Serono SA (CH) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093557-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | LABORATOIRES SERONO S.A. (CH) | 2007-08-23 | — | — | WO | disclosed |