Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4713475 | 0.87 | MAPT (0.35) | MAPTEPHX1ELANETP53TRPV1 | |
| SCHEMBL4716661 | 0.83 | MAPT (0.37) | MAPTEPHX1ELANETP53TRPV1 | |
| SCHEMBL4711910 | 0.81 | MAPT (0.40) | MAPTEPHX1ELANETRPV1POLB | |
| SCHEMBL4711906 | 0.81 | EPHX1 (0.38) | MAPTEPHX1ELANETRPV1ALDH1A1 | |
| SCHEMBL5047436 | 0.80 | MAPT (0.36) | MAPTELANETP53ALDH1A1KMT2A | |
| SCHEMBL4713478 | 0.79 | NR1D1 (0.38) | MAPTEPHX1TRPV1ALDH1A1KMT2A | |
| SCHEMBL4022922 | 0.77 | EPHX1 (0.39) | MAPTEPHX1TRPV1ALDH1A1TSHR | |
| SCHEMBL4714867 | 0.76 | KMT2A (0.49) | EPHX1TP53ALDH1A1KMT2ATSHR | |
| SCHEMBL5040028 | 0.74 | ACP3 (0.43) | MAPTELANETP53ALDH1A1TSHR | |
| SCHEMBL4711947 | 0.74 | TSHR (0.41) | MAPTTP53ALDH1A1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986637-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | Laboratoires Serono SA (CH) | 2008-11-05 | — | — | EP | claimed |
| WO-2007093557-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | LABORATOIRES SERONO S.A. (CH) | 2007-08-23 | — | — | WO | claimed |