SCHEMBL4714924

SCHEMBL4714924

O=C1c2c(nn(-c3cccc(Cl)c3)c2-c2ccc(Cl)cc2)CCN1C1CCCCC1

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 16/20 0.52
CNR2 P34972 1/20 0.52
SRC P12931 2/20 0.50
GRM5 P41594 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4713165 0.90 SRC (0.47) CNR1CNR2SRCGRM5
SCHEMBL4711471 0.86 CNR1 (0.64) CNR1CNR2
SCHEMBL4711661 0.84 CNR1 (0.71) CNR1CNR2
SCHEMBL4714926 0.80 SRC (0.47) SRC
SCHEMBL4715388 0.78 CNR1 (0.49) CNR1CNR2SRCGRM5
SCHEMBL4715084 0.76 CNR1 (0.52) CNR1CNR2SRC
SCHEMBL4713271 0.76 CNR1 (0.56) CNR1CNR2
SCHEMBL4712094 0.74 GRM5 (0.49) CNR1CNR2GRM5
SCHEMBL4714457 0.73 CNR1 (0.62) CNR1CNR2
SCHEMBL4713168 0.73 SRC (0.47) SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040214856-A1 Cannabinoid receptor ligands and uses thereof PFIZER INC 2004-10-28 US claimed
EP-1622903-B1 CANNABINOID RECEPTOR LIGANDS AND USES THEREOF PFIZER PROD INC (US) 2008-10-01 EP disclosed
EP-1622903-A1 CANNABINOID RECEPTOR LIGANDS AND USES THEREOF Pfizer Products Inc. (US) 2006-02-08 EP disclosed
WO-2004094421-A1 CANNABINOID RECEPTOR LIGANDS AND USES THEREOF PFIZER PRODUCTS INC. (US) 2004-11-04 WO disclosed
US-20040214856-A1 Cannabinoid receptor ligands and uses thereof PFIZER INC 2004-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040214856-A1 Cannabinoid receptor ligands and uses thereof CNR1, CNR2, GPR18 CNR1 1/4885CNR2 2/4885SRC 1876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.