Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 6/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4514161 | 0.95 | KDM4D (0.39) | KDM4DSUV39H2KAT8CTSKJAK3 | |
| SCHEMBL4516315 | 0.92 | BTK (0.40) | KDM4DSUV39H2KAT8CTSKJAK3 | |
| SCHEMBL4502626 | 0.90 | KDM4D (0.40) | KDM4DSUV39H2CTSKJAK3BTK | |
| SCHEMBL4502633 | 0.90 | KDM4D (0.40) | KDM4DSUV39H2CTSKJAK3BTK | |
| SCHEMBL4506885 | 0.87 | BTK (0.39) | KDM4DCTSKJAK3BTKPIM1 | |
| SCHEMBL4515747 | 0.86 | DRD2 (0.40) | KDM4DMCL1SUV39H2CTSKJAK3 | |
| SCHEMBL4515754 | 0.86 | DRD2 (0.40) | KDM4DMCL1SUV39H2CTSKJAK3 | |
| SCHEMBL4515639 | 0.85 | JAK3 (0.40) | KDM4DSUV39H2KAT8CTSKJAK3 | |
| SCHEMBL7554372 | 0.84 | KDM4D (0.38) | KDM4DSUV39H2CTSKJAK3BTK | |
| SCHEMBL4515547 | 0.83 | KAT8 (0.38) | KDM4DKAT8KAT6AKAT5BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255739-B1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER LAMBERT CO (US) | 2008-06-11 | — | — | EP | disclosed |