Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 4/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | BRS3 | P32247 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13015198 | 1.00 | GFER (0.41) | GFERCASP6HTTBRS3ALDH1A1 | |
| SCHEMBL4715449 | 0.90 | SMN1; SMN2 (0.44) | GFERCASP6BRS3ALDH1A1MAPT | |
| SCHEMBL7029894 | 0.86 | SYK (0.44) | GFERCASP6HTTALDH1A1MAPT | |
| SCHEMBL5702089 | 0.83 | NOTUM (0.49) | ALDH1A1KMT2AMEN1NOTUMSIGMAR1 | |
| SCHEMBL5702158 | 0.83 | NOTUM (0.49) | ALDH1A1KMT2AMEN1NOTUMSIGMAR1 | |
| SCHEMBL20458161 | 0.82 | NOTUM (0.53) | ALDH1A1MAPTGAAKDM4EKMT2A | |
| SCHEMBL2121761 | 0.82 | NOTUM (0.53) | GFERHTTALDH1A1MAPTKMT2A | |
| SCHEMBL9891645 | 0.82 | NOTUM (0.53) | ALDH1A1MAPTGAAKDM4EKMT2A | |
| SCHEMBL2121764 | 0.82 | NOTUM (0.53) | GFERHTTALDH1A1MAPTKMT2A | |
| SCHEMBL27634306 | 0.79 | FKBP1A (0.40) | GFERCASP6HTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030028976-A1 | Compositions for dyeing keratinic fibres, containing paraphenylenediamine derivatives with an azetidinyl group | L'OREAL S.A. (FR) | 2003-02-13 | — | — | US | claimed |
| US-20030028976-A1 | Compositions for dyeing keratinic fibres, containing paraphenylenediamine derivatives with an azetidinyl group | L'OREAL S.A. (FR) | 2003-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030028976-A1 | Compositions for dyeing keratinic fibres, containing paraphenylenediamine derivatives with an azetidinyl group | KRT18, CDC73, AOC1 | GFER 1850/4885CASP6 2908/4885HTT 3226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.