SCHEMBL4715641

SCHEMBL4715641

CC(C)N1Cc2nn(-c3cccc(Cl)c3)c(-c3ccc(Cl)cc3)c2C1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 7/20 0.48
CNR1 P21554 3/20 0.41
PPP1CA P62136 1/20 0.40
LMNA P02545 2/20 0.38
GAA P10253 2/20 0.38
MAPT P10636 2/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
CRHBP P24387 1/20 0.38
HTT P42858 1/20 0.38
CRHR2 Q13324 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NOD2 Q9HC29 1/20 0.38
CNR2 P34972 1/20 0.38
XIAP P98170 1/20 0.38
BIRC2 Q13490 1/20 0.38
ALPG P10696 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
GRM1 Q13255 1/20 0.36
ATM Q13315 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4715388 0.89 CNR1 (0.49) SRCCNR1PPP1CALMNAGAA
SCHEMBL4711441 0.84 CNR1 (0.48) CNR1CNR2
SCHEMBL4714742 0.82 CNR1 (0.61) CNR1CNR2
SCHEMBL4713168 0.82 SRC (0.47) SRCPPP1CAGAAKMT2AMEN1
SCHEMBL4714991 0.78 CNR1 (0.45) SRCCNR1PPP1CA
SCHEMBL4713165 0.78 SRC (0.47) SRCCNR1CNR2GRM5
SCHEMBL4714926 0.76 SRC (0.47) SRCPPP1CAKMT2AMEN1SMN1; SMN2
SCHEMBL4715084 0.74 CNR1 (0.52) SRCCNR1PPP1CACNR2
SCHEMBL4712910 0.72 CNR1 (0.50) SRCCNR1SMN1; SMN2CNR2
SCHEMBL4714656 0.72 CNR1 (0.71) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040214856-A1 Cannabinoid receptor ligands and uses thereof PFIZER INC 2004-10-28 US claimed
EP-1622903-B1 CANNABINOID RECEPTOR LIGANDS AND USES THEREOF PFIZER PROD INC (US) 2008-10-01 EP disclosed
EP-1622903-A1 CANNABINOID RECEPTOR LIGANDS AND USES THEREOF Pfizer Products Inc. (US) 2006-02-08 EP disclosed
WO-2004094421-A1 CANNABINOID RECEPTOR LIGANDS AND USES THEREOF PFIZER PRODUCTS INC. (US) 2004-11-04 WO disclosed
US-20040214856-A1 Cannabinoid receptor ligands and uses thereof PFIZER INC 2004-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040214856-A1 Cannabinoid receptor ligands and uses thereof CNR1, CNR2, GPR18 SRC 1876/4885CNR1 1/4885PPP1CA 3515/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.