SCHEMBL4715815

SCHEMBL4715815

CCCCCCCCCCCCNS(=O)(=O)c1ccc(C)s1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.71
SMN1; SMN2 Q16637 3/20 0.71
HTT P42858 2/20 0.71
MEN1 O00255 2/20 0.71
TSHR P16473 2/20 0.71
RECQL P46063 1/20 0.49
ALDH1A1 P00352 4/20 0.47
MAPK1 P28482 2/20 0.46
LMNA P02545 2/20 0.46
TP53 P04637 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C19 P33261 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
POLB P06746 1/20 0.45
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
PPARA Q07869 2/20 0.43
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11051510 0.94 KMT2A (0.61) KMT2ASMN1; SMN2HTTMEN1TSHR
SCHEMBL4715407 0.83 SMN1; SMN2 (0.69) KMT2ASMN1; SMN2HTTMEN1TSHR
SCHEMBL4715813 0.83 KMT2A (0.69) KMT2ASMN1; SMN2HTTMEN1TSHR
SCHEMBL1853154 0.81 KMT2A (0.66) KMT2ASMN1; SMN2HTTMEN1TSHR
SCHEMBL4715831 0.76 TSHR (0.60) KMT2ASMN1; SMN2HTTMEN1TSHR
SCHEMBL4716454 0.76 TSHR (0.43) KMT2ASMN1; SMN2HTTMEN1TSHR
SCHEMBL27601052 0.75 CYP2D6 (0.70) KMT2ASMN1; SMN2HTTMEN1TSHR
SCHEMBL4714784 0.75 KMT2A (0.62) KMT2ASMN1; SMN2HTTMEN1TSHR
SCHEMBL4714622 0.74 TSHR (0.56) KMT2ASMN1; SMN2HTTMEN1TSHR
SCHEMBL1856043 0.74 SMN1; SMN2 (0.56) KMT2ASMN1; SMN2HTTMEN1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1986637-A1 SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS Laboratoires Serono SA (CH) 2008-11-05 EP claimed
WO-2007093557-A1 SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS LABORATOIRES SERONO S.A. (CH) 2007-08-23 WO claimed