SCHEMBL4715813

SCHEMBL4715813

[CH2]c1ccc(S(=O)(=O)NCCCCCCCCCCCC)s1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.69
SMN1; SMN2 Q16637 3/20 0.69
TSHR P16473 3/20 0.69
HTT P42858 2/20 0.69
MEN1 O00255 2/20 0.69
RECQL P46063 1/20 0.48
ALDH1A1 P00352 6/20 0.46
MAPK1 P28482 2/20 0.45
LMNA P02545 2/20 0.45
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C19 P33261 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
PPARA Q07869 2/20 0.42
POLB P06746 1/20 0.41
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4715815 0.83 KMT2A (0.71) KMT2ASMN1; SMN2TSHRHTTMEN1
SCHEMBL4715407 0.82 SMN1; SMN2 (0.69) KMT2ASMN1; SMN2TSHRHTTMEN1
SCHEMBL1853154 0.79 KMT2A (0.66) KMT2ASMN1; SMN2TSHRHTTMEN1
SCHEMBL11051510 0.76 KMT2A (0.61) KMT2ASMN1; SMN2TSHRHTTMEN1
SCHEMBL4716453 0.76 TSHR (0.42) KMT2ASMN1; SMN2TSHRHTTMEN1
SCHEMBL4715831 0.75 TSHR (0.60) KMT2ASMN1; SMN2TSHRHTTMEN1
SCHEMBL4714784 0.74 KMT2A (0.62) KMT2ASMN1; SMN2TSHRHTTMEN1
SCHEMBL27601052 0.74 CYP2D6 (0.70) KMT2ASMN1; SMN2TSHRHTTMEN1
SCHEMBL4714622 0.72 TSHR (0.56) KMT2ASMN1; SMN2TSHRHTTMEN1
SCHEMBL1856043 0.72 SMN1; SMN2 (0.56) KMT2ASMN1; SMN2TSHRHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1986637-A1 SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS Laboratoires Serono SA (CH) 2008-11-05 EP claimed
WO-2007093557-A1 SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS LABORATOIRES SERONO S.A. (CH) 2007-08-23 WO claimed