Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4136931 | 0.87 | KMT2A (0.47) | KMT2AMEN1MAPTHTTLMNA | |
| SCHEMBL4136928 | 0.87 | KMT2A (0.47) | KMT2AMEN1MAPTHTTLMNA | |
| SCHEMBL4140178 | 0.84 | KMT2A (0.52) | KMT2AMEN1MAPTHTTLMNA | |
| SCHEMBL4140176 | 0.84 | KMT2A (0.52) | KMT2AMEN1MAPTHTTLMNA | |
| SCHEMBL4128887 | 0.83 | LMNA (0.59) | KMT2AMEN1MAPTHTTLMNA | |
| SCHEMBL4128884 | 0.83 | LMNA (0.59) | KMT2AMEN1MAPTHTTLMNA | |
| SCHEMBL4145485 | 0.82 | KMT2A (0.71) | KMT2AMEN1MAPTHTTLMNA | |
| SCHEMBL4145482 | 0.82 | KMT2A (0.71) | KMT2AMEN1MAPTHTTLMNA | |
| SCHEMBL4136140 | 0.80 | KMT2A (0.58) | KMT2AMEN1MAPTHTTLMNA | |
| SCHEMBL4136143 | 0.80 | KMT2A (0.58) | KMT2AMEN1MAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1906955-A2 | USE OF THIAZOLE DERIVATIVES AND ANALOGUES IN THE TREATMENT OF CANCER | Betagenon AB (SE) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007010273-A2 | USE OF THIAZOLE DERIVATIVES AND ANALOGUES IN THE TREATMENT OF CANCER | BETAGENON AB (SE) | 2007-01-25 | — | — | WO | disclosed |