Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13068145 | 0.87 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL30294843 | 0.85 | ALDH1A1 (0.43) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL2036018 | 0.85 | ALDH1A1 (0.40) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL13351316 | 0.85 | ALDH1A1 (0.43) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL15721000 | 0.83 | ALDH1A1 (0.39) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL2685253 | 0.83 | HSP90AA1 (0.43) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL31043000 | 0.83 | ALDH1A1 (0.39) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL29983622 | 0.83 | HSP90AA1 (0.43) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL15938139 | 0.81 | PIK3CA (0.40) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL151590 | 0.80 | ALDH1A1 (0.59) | ALDH1A1NPC1RAB9AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535865-A | High-performance rubber-plastic composite material and preparation method thereof | 慈溪市源盛橡塑有限公司 | 2023-08-04 | — | — | CN | claimed |
| CN-109293582-A | A kind of preparation method of synthesis 4- amino -2,6- dimethoxypyridin | 江苏天和制药有限公司 | 2019-02-01 | — | — | CN | claimed |
| CN-109232441-A | preparation method of 4-amino-2, 6-dimethoxypyrimidine | 南京工业大学 | 2019-01-18 | — | — | CN | claimed |
| CN-108929278-A | A kind of preparation method of 4- amino -2,6- dimethoxypyridin | 江苏天和制药有限公司 | 2018-12-04 | — | — | CN | claimed |
| CN-207944040-U | A kind of 4- amino -2.6- dimethoxypyridin solvent methanol reclaimers | 连云港市国盛化工有限公司 | 2018-10-09 | — | — | CN | claimed |
| CN-105646373-B | A kind of preparation method of 4- amino -2,6- dimethoxypyridins | 滨海新东方医化有限公司 | 2018-05-29 | — | — | CN | claimed |
| CN-107325057-A | A kind of preparation method of the dimethoxypyridin of sulfanilamide (SN) 2,6 | 吴赣药业（苏州）有限公司 | 2017-11-07 | — | — | CN | claimed |
| CN-105646373-A | Preparation method of 4-amino-2,6-dimethoxypyrimidine | 滨海新东方医化有限公司 | 2016-06-08 | — | — | CN | claimed |
| CN-101928943-B | Compound corrosion inhibitor for butyl rubber chloromethane glycol dehydrating regeneration system | CHINA PETROLEUM & CHEMICAL | 2013-01-16 | — | — | CN | claimed |
| CN-102650056-A | Composite corrosion inhibitor for butyl rubber chloromethane glycol dehydration and regeneration system | CHINA PETROLEUM & CHEMICAL | 2012-08-29 | — | — | CN | claimed |
| CN-102650058-A | Composite corrosion inhibitor for butyl rubber chloromethane glycol dehydration and regeneration system | CHINA PETROLEUM & CHEMICAL | 2012-08-29 | — | — | CN | claimed |
| CN-101928942-A | Composite corrosion inhibitor of butyl rubber chloromethane glycol dehydration regeneration system | CHINA PETROLEUM & CHEMICAL | 2010-12-29 | — | — | CN | claimed |
| CN-101928943-A | Compound corrosion inhibitor for butyl rubber chloromethane glycol dehydrating regeneration system | CHINA PETROLEUM & CHEMICAL | 2010-12-29 | — | — | CN | claimed |
| EP-4482579-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH LPA RECEPTOR ACTIVITY | LHOTSE BIO INC (US) | 2026-02-18 | — | — | EP | disclosed |
| US-12428375-B2 | Compounds and compositions for treating conditions associated with LPA receptor activity | LHOTSE BIO, INC. (US) | 2025-09-30 | — | — | US | disclosed |
| EP-4482579-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH LPA RECEPTOR ACTIVITY | Lhotse Bio, Inc. (US) | 2025-01-01 | — | — | EP | disclosed |
| US-7022711-B2 | 2-(4-Pyridyl)amino-6-dialkoxyphenyl-pyrido[2,3-d]pyrimidin-7-ones | WARNER-LAMBERT COMPANY (US) | 2006-04-04 | — | — | US | disclosed |
| US-20030220345-A1 | 2-(4-Pyridyl)amino-6-dialkoxyphenyl-pyrido[2,3-d]pyrimdin-7-ones | HAMBY JAMES MARINO (US) | 2003-11-27 | — | — | US | disclosed |
| EP-1307450-A2 | 2-(4-PYRDYL)AMINO-6-DIALKOXYPHENYL-PYRIDO(2.3-D)PYRIMIDIN-7-ONES | WARNER-LAMBERT COMPANY (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002012238-A2 | 2-(4-PYRIDYL)AMINO-6-DIALKOXYPHENYL-PYRIDO[2,3-d]PYRIMIDIN-7-ONES | WARNER-LAMBERT COMPANY (US) | 2002-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220345-A1 | 2-(4-Pyridyl)amino-6-dialkoxyphenyl-pyrido[2,3-d]pyrimdin-7-ones | FLT1, FLT4, MKI67 | ALDH1A1 930/4885NPC1 3488/4885RAB9A 1986/4885 |
| US-12428375-B2 | Compounds and compositions for treating conditions associated with LPA receptor activity | LPAR2, LPAR1, LPAR6 | ALDH1A1 1863/4885NPC1 90/4885RAB9A 914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.