SCHEMBL4716473

SCHEMBL4716473

[CH2]C(CCCC)NC(C)=O

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PLA2G2C Q5R387 7/20 0.50
CA2 P00918 5/20 0.39
CA1 P00915 4/20 0.39
MAPK1 P28482 1/20 0.39
SIRT6 Q8N6T7 1/20 0.38
SIRT1 Q96EB6 1/20 0.38
PLA2G2A P14555 1/20 0.37
ALDH1A1 P00352 1/20 0.37
DPP8 Q6V1X1 2/20 0.37
DPP7 Q9UHL4 2/20 0.37
DPP4 P27487 1/20 0.37
DPP9 Q86TI2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20211076 1.00 PLA2G2C (0.50) PLA2G2CCA2CA1MAPK1SIRT6
SCHEMBL10529631 0.92 PLA2G2C (0.51) PLA2G2CMAPK1SIRT6SIRT1PLA2G2A
SCHEMBL9616824 0.86
SCHEMBL15528876 0.83 TRPV1 (0.35) PLA2G2CMAPK1ALDH1A1
SCHEMBL6547737 0.77 PLA2G2C (0.62) PLA2G2CCA2CA1PLA2G2ADPP8
SCHEMBL200454 0.77
SCHEMBL10617016 0.77
SCHEMBL6218251 0.77
SCHEMBL9386616 0.76 PLA2G2C (0.36) PLA2G2CMAPK1
SCHEMBL2760205 0.76 TAS1R3 (0.50) PLA2G2CCA2CA1MAPK1DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110099567-A Antimicrobial insect repellant compositions 耶迪特普大学 2019-08-06 CN disclosed
CN-206884297-U A kind of family's cabinet fiberboard 湖北吉象人造林制品有限公司 2018-01-16 CN disclosed
EP-1957073-A2 MEDICINAL DRUG OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2008-08-20 EP disclosed
WO-2007066784-A2 DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-06-14 WO disclosed