Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.59 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MLYCD | O95822 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22351334 | 0.90 | HPGD (0.59) | HPGDTDP1LMNASMN1; SMN2MEN1 | |
| SCHEMBL18661938 | 0.85 | HPGD (0.68) | HPGDTDP1LMNASMN1; SMN2MEN1 | |
| SCHEMBL4545228 | 0.85 | HSP90AA1 (0.70) | HPGDTDP1LMNASMN1; SMN2MEN1 | |
| SCHEMBL10156527 | 0.84 | HPGD (0.66) | HPGDTDP1LMNASMN1; SMN2MEN1 | |
| SCHEMBL471664 | 0.84 | HPGD (0.66) | HPGDTDP1LMNASMN1; SMN2MEN1 | |
| SCHEMBL14426602 | 0.84 | HSP90AA1 (0.66) | HPGDTDP1LMNASMN1; SMN2MEN1 | |
| SCHEMBL17877005 | 0.84 | HPGD (0.61) | HPGDTDP1LMNASMN1; SMN2MEN1 | |
| SCHEMBL11699200 | 0.84 | HPGD (0.66) | HPGDTDP1LMNASMN1; SMN2MEN1 | |
| SCHEMBL30786345 | 0.84 | HPGD (0.66) | HPGDTDP1LMNASMN1; SMN2MEN1 | |
| SCHEMBL9299563 | 0.84 | HPGD (0.76) | HPGDTDP1LMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160219878-A1 | Repellent Compositions for Insects and Other Arthropods | INTERNATIONAL CENTRE OF INSECT PHYSIOLOGY AND ECOLOGY (KE) | 2016-08-04 | — | — | US | disclosed |
| EP-3030076-A2 | REPELLENT COMPOSITIONS FOR INSECTS AND OTHER ARTHROPODS | International Centre of Insect and Physiology and Ecology (KE) | 2016-06-15 | — | — | EP | disclosed |
| WO-2015020239-A2 | REPELLENT COMPOSITIONS FOR INSECTS AND OTHER ARTHROPODS | INTERNATIONAL CENTRE OF INSECT AND PHYSIOLOGY AND ECOLOGY (KE) | 2015-02-12 | — | — | WO | disclosed |
| US-8703768-B2 | Nitrogen containing heteroaryl compounds | HOFFMANN-LA ROCHE INC. (US) | 2014-04-22 | — | — | US | disclosed |
| US-8623866-B2 | — | — | 2014-01-07 | — | — | US | disclosed |
| US-20110306589-A1 | NITROGEN CONTAINING HETEROARYL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-12-15 | — | — | US | disclosed |
| US-7829741-B2 | Process for producing α, α-difluoroamine | NATIONAL UNIVERSITY CORPORATION (JP) | 2010-11-09 | — | — | US | disclosed |
| US-20090177012-A1 | PROCESS FOR PRODUCING ALPHA, ALPHA-DIFLUOROAMINE | NATIONAL UNIVERSITY CORPORATION, HOKKAIDO UNIVERSITY (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-1813596-A1 | PROCESS FOR PRODUCING ALPHA, ALPHA- DIFLUOROAMINE | National University Corporation Hokkaido University (JP) | 2007-08-01 | — | — | EP | disclosed |
| US-6562841-B1 | Testing each stereoisomer of a piperidine analog for its effectiveness as an arthropod repellent against an arthropod, comparing the test results and selecting the most effective arthropod repellent stereoisomer | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2003-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160219878-A1 | Repellent Compositions for Insects and Other Arthropods | C5, C3AR1, C5AR1 | HPGD 4553/4885TDP1 4529/4885LMNA 4743/4885 |
| US-20110306589-A1 | NITROGEN CONTAINING HETEROARYL COMPOUNDS | PDE10A, PDE3A, PDE2A | HPGD 603/4885TDP1 285/4885LMNA 2125/4885 |
| US-20090177012-A1 | PROCESS FOR PRODUCING ALPHA, ALPHA-DIFLUOROAMINE | FUCA1, FUCA2, DBH | HPGD 1246/4885TDP1 1729/4885LMNA 4155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.