Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 4/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 6/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL843676 | 0.80 | CETP (0.57) | CETPKCNH2 | |
| SCHEMBL843677 | 0.80 | CETP (0.57) | CETPKCNH2 | |
| SCHEMBL843674 | 0.80 | CETP (0.57) | CETPKCNH2 | |
| SCHEMBL843675 | 0.80 | CETP (0.57) | CETPKCNH2 | |
| SCHEMBL4969174 | 0.76 | CETP (0.48) | P2RX1CETPKCNH2SLC6A9TACR1 | |
| SCHEMBL4721472 | 0.74 | CETP (0.41) | P2RX1CETPKCNH2SLC6A9HTT | |
| SCHEMBL4966775 | 0.73 | CETP (0.43) | P2RX1CETPKCNH2SLC6A9TACR1 | |
| SCHEMBL4967551 | 0.73 | CETP (0.43) | P2RX1CETPKCNH2SLC6A9TACR1 | |
| SCHEMBL4970220 | 0.73 | CETP (0.43) | P2RX1CETPKCNH2SLC6A9TACR1 | |
| SCHEMBL4971187 | 0.72 | CETP (0.65) | P2RX1CETPKCNH2SLC6A9TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951690-A1 | HETEROCYCLIC CETP INHIBITORS | Brystol-Myers Squibb Company (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007062342-A1 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |