Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 6/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | MAX | P61244 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4717108 | 0.81 | CETP (0.50) | CETPKCNH2 | |
| SCHEMBL4969174 | 0.80 | CETP (0.48) | CETPALDH1A1LMNAL3MBTL1KCNN4 | |
| SCHEMBL4967551 | 0.77 | CETP (0.43) | CETPKCNH2SLC6A9P2RX1 | |
| SCHEMBL4966775 | 0.77 | CETP (0.43) | CETPKCNH2SLC6A9P2RX1 | |
| SCHEMBL4970220 | 0.77 | CETP (0.43) | CETPKCNH2SLC6A9P2RX1 | |
| SCHEMBL4971187 | 0.74 | CETP (0.65) | CETPALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL4716662 | 0.74 | DDR1 (0.40) | CETPLMNAL3MBTL1POLBKCNH2 | |
| SCHEMBL843539 | 0.73 | CETP (0.64) | CETPCTSLCTSBKCNH2 | |
| SCHEMBL843538 | 0.73 | CETP (0.64) | CETPCTSLCTSBKCNH2 | |
| SCHEMBL4969024 | 0.72 | CETP (0.66) | CETPALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951690-A1 | HETEROCYCLIC CETP INHIBITORS | Brystol-Myers Squibb Company (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007062342-A1 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |