Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 17/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 15/20 | 0.55 |
| ▸ | DRD2 | P14416 | 14/20 | 0.55 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4717812 | 0.99 | ADRB2 (0.55) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL4720983 | 0.90 | ADRB2 (0.68) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL4719298 | 0.90 | ADRB2 (0.69) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL4715374 | 0.88 | ADRB2 (0.68) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL4716723 | 0.88 | ADRB2 (0.61) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL4761291 | 0.87 | ADRB2 (0.57) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL4557985 | 0.87 | ADRB2 (0.70) | ADRB2ADRB1ADRA1DDRD2 | |
| Hydrochloric Acid SCHEMBL4715379 | 0.86 | ADRB2 (0.69) | ADRB2ADRB1ADRA1DDRD2 | |
| SCHEMBL4714954 | 0.86 | ADRB2 (0.68) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL4712112 | 0.86 | ADRB2 (0.59) | ADRB2ADRB1ADRA1DDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996566-A1 | BEZOTHIAZOL DERIVATIVES AS BETA2 ADRENORECEPTOR AGONISTS | AstraZeneca AB (SE) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007106016-A1 | BEZOTHIAZOL DERIVATIVES AS BETA2 ADRENORECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2007-09-20 | — | — | WO | disclosed |