Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | RRM1 | P23921 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14273835 | 1.00 | CASP2 (0.50) | CASP2EPHX1NAAAFAAHACE2 | |
| SCHEMBL14414107 | 1.00 | CASP2 (0.50) | CASP2EPHX1NAAAFAAHACE2 | |
| SCHEMBL9321698 | 0.87 | CASP2 (0.56) | CASP2EPHX1NAAAFAAHRRM1 | |
| SCHEMBL10629979 | 0.84 | BLM (0.44) | NAAACNR1BLM | |
| SCHEMBL62131 | 0.82 | BLM (0.46) | CNR1BLM | |
| SCHEMBL24047859 | 0.81 | CASP2 (0.62) | CASP2EPHX1NAAAFAAHMMP8 | |
| SCHEMBL15855111 | 0.81 | CASP2 (0.62) | CASP2EPHX1NAAAFAAHMMP8 | |
| SCHEMBL15855158 | 0.81 | CASP2 (0.62) | CASP2EPHX1NAAAFAAHMMP8 | |
| SCHEMBL15855095 | 0.81 | CASP2 (0.62) | CASP2EPHX1NAAAFAAHMMP8 | |
| SCHEMBL18231905 | 0.81 | CNR1 (0.56) | CASP2NAAAFAAHCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101404985-A | Autoimmune conditions and NADPH oxidase defects | BIOVITRUM AB PUBL (SE) | 2009-04-08 | — | — | CN | disclosed |
| EP-2004159-A1 | AUTOIMMUNE CONDITIONS AND NADPH OXIDASE DEFECTS | Biovitrum AB (publ) (SE) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007104790-A1 | AUTOIMMUNE CONDITIONS AND NADPH OXIDASE DEFECTS | BIOVITRUM AB (PUBL) (SE) | 2007-09-20 | — | — | WO | disclosed |