Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 8/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 4/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14005022 | 0.81 | CYP1A2 (0.36) | CYP1A2CYP3A4TSHRCYP2C9CLK4 | |
| SCHEMBL1890488 | 0.78 | CYP1A2 (0.39) | CYP1A2CYP2C9CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL5225579 | 0.75 | — | — | |
| SCHEMBL4166555 | 0.73 | TGM2 (0.32) | — | |
| SCHEMBL14608888 | 0.73 | PLK4 (0.38) | — | |
| SCHEMBL4164860 | 0.73 | PLK4 (0.38) | — | |
| SCHEMBL14621115 | 0.73 | CDC7 (0.36) | CLK4SMN1; SMN2 | |
| SCHEMBL1889868 | 0.73 | CDC7 (0.36) | CLK4SMN1; SMN2 | |
| SCHEMBL1884372 | 0.66 | GSK3B (0.46) | CYP1A2SMN1; SMN2 | |
| SCHEMBL4164922 | 0.63 | NOTUM (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287472-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-20 | — | — | US | disclosed |
| US-20080287472-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-20 | — | — | US | disclosed |
| US-20080287472-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-20 | — | — | US | disclosed |
| EP-1575949-B1 | FUNGICIDES | SYNGENTA LTD (GB) | 2008-04-02 | — | — | EP | disclosed |
| US-20070066605-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. | 2007-03-22 | — | — | US | disclosed |
| US-20070066605-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. | 2007-03-22 | — | — | US | disclosed |
| US-20070066605-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. | 2007-03-22 | — | — | US | disclosed |
| EP-1575949-A1 | FUNGICIDES | Syngenta Limited (GB) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004056826-A1 | FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287472-A1 | Fungicides | PNPO, CYP4X1, CYP1A2 | CYP1A2 3/4885CYP3A4 12/4885TSHR 3611/4885 |
| US-20070066605-A1 | Fungicides | CYP4X1, CYP4F8, CBR3 | CYP1A2 26/4885CYP3A4 21/4885TSHR 93/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.