Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.79 |
| ▸ | ADRB1 | P08588 | 18/20 | 0.79 |
| ▸ | ADRA1D | P25100 | 17/20 | 0.79 |
| ▸ | DRD2 | P14416 | 15/20 | 0.79 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4714831 | 0.94 | ADRB2 (0.81) | ADRB2ADRB1ADRA1DDRD2 | |
| SCHEMBL4557989 | 0.93 | ADRB2 (0.80) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL4714223 | 0.90 | ADRB2 (0.81) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL1801962 | 0.88 | ADRB2 (1.00) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL1801961 | 0.88 | ADRB2 (1.00) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL1800615 | 0.88 | ADRB2 (0.98) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL1800618 | 0.88 | ADRB2 (0.98) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL4789947 | 0.86 | ADRB2 (0.75) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL1801963 | 0.86 | ADRB2 (0.72) | ADRB2ADRB1ADRA1DDRD2 | |
| Hydrochloric Acid SCHEMBL1800620 | 0.85 | ADRB2 (0.71) | ADRB2ADRB1ADRA1DDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996566-A1 | BEZOTHIAZOL DERIVATIVES AS BETA2 ADRENORECEPTOR AGONISTS | AstraZeneca AB (SE) | 2008-12-03 | — | — | EP | claimed |
| WO-2007106016-A1 | BEZOTHIAZOL DERIVATIVES AS BETA2 ADRENORECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2007-09-20 | — | — | WO | claimed |