⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468282 | 1.00 | — | — | |
| SCHEMBL471705 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL9978591 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL9980432 | 0.97 | — | — | |
| SCHEMBL470793 | 0.83 | — | — | |
| SCHEMBL17928983 | 0.82 | — | — | |
| SCHEMBL11825568 | 0.82 | — | — | |
| SCHEMBL21261786 | 0.80 | — | — | |
| SCHEMBL19445459 | 0.80 | — | — | |
| SCHEMBL13357074 | 0.78 | THRB (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007091110-A1 | ENZYMATIC RESOLUTION PROCESS FOR THE PREPARATION OF CYCLI-C BETA-AMINO ACID AND ESTER ENATIOMERS | SZEGEDI TUDOMANYEGYETEM (HU) | 2007-08-16 | — | — | WO | claimed |
| US-8987498-B2 | Enantiomerically pure amines | NABRIVA THERAPEUTICS AG (AT) | 2015-03-24 | — | — | US | disclosed |
| US-8987498-B2 | Enantiomerically pure amines | NABRIVA THERAPEUTICS AG (AT) | 2015-03-24 | — | — | US | disclosed |
| EP-2576531-B1 | Enantiomerically pure amines | NABRIVA THERAPEUTICS AG (AT) | 2014-08-13 | — | — | EP | disclosed |
| US-20130072711-A1 | ENANTIOMERICALLY PURE AMINES | NABRIVA THERAPEUTICS AG (AT) | 2013-03-21 | — | — | US | disclosed |
| US-20130072711-A1 | ENANTIOMERICALLY PURE AMINES | NABRIVA THERAPEUTICS AG (AT) | 2013-03-21 | — | — | US | disclosed |
| WO-2011146953-A1 | ENANTIOMERICALLY PURE AMINES | NABRIVA THERAPEUTICS AG (AT) | 2011-12-01 | — | — | WO | disclosed |
| EP-2390245-A1 | Enantiomerically pure amines | Nabriva Therapeutics AG (AT) | 2011-11-30 | — | — | EP | disclosed |