Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27859313 | 0.81 | HSPB1 (0.82) | HSPB1MEN1KMT2AGAAPKM | |
| SCHEMBL4717656 | 0.81 | PARP10 (0.37) | HSPB1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3139234 | 0.79 | KMT2A (0.74) | HSPB1MEN1KMT2AGAAPKM | |
| SCHEMBL3131710 | 0.79 | HSPB1 (0.68) | HSPB1MEN1KMT2AGAAPKM | |
| SCHEMBL31287841 | 0.79 | HSPB1 (0.82) | HSPB1MEN1KMT2AGAAPKM | |
| SCHEMBL5172280 | 0.78 | HSPB1 (0.56) | HSPB1MEN1KMT2AGAAPKM | |
| SCHEMBL5167784 | 0.77 | HSPB1 (0.62) | HSPB1MEN1KMT2AGAAPKM | |
| SCHEMBL22069708 | 0.76 | HSPB1 (0.68) | HSPB1MEN1KMT2AGAAPKM | |
| SCHEMBL22069702 | 0.76 | HSPB1 (0.68) | HSPB1MEN1KMT2AGAAPKM | |
| SCHEMBL29351876 | 0.76 | HSPB1 (0.68) | HSPB1MEN1KMT2AGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957073-A2 | MEDICINAL DRUG | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007066784-A2 | DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-06-14 | — | — | WO | disclosed |