Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.30 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3856288 | 0.95 | CNR1 (0.34) | KDM2BKDM4CCSNK1DCSNK1E | |
| SCHEMBL4717283 | 0.85 | KDM2B (0.38) | KDM2BKDM4CCSNK1DCSNK1E | |
| SCHEMBL5852284 | 0.79 | — | — | |
| SCHEMBL3856284 | 0.79 | KDM2B (0.38) | KDM2BKDM4CCSNK1DCSNK1E | |
| SCHEMBL5852256 | 0.77 | ATM (0.32) | — | |
| SCHEMBL3847279 | 0.76 | CCR3 (0.36) | — | |
| SCHEMBL3847835 | 0.75 | ALOX5AP (0.37) | — | |
| SCHEMBL3847150 | 0.75 | FGFR1 (0.33) | — | |
| SCHEMBL3846716 | 0.74 | POLB (0.33) | — | |
| SCHEMBL3847629 | 0.74 | CSNK1D (0.33) | CSNK1DCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1382603-B1 | NITROGENOUS FUSED-RING COMPOUND HAVING PYRAZOLYL GROUP AS SUBSTITUENT AND MEDICINAL COMPOSITION THEREOF | EISAI R&D MAN CO LTD (JP) | 2008-07-23 | — | — | EP | disclosed |
| US-7074801-B1 | Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof | EISAI CO., LTD. (JP) | 2006-07-11 | — | — | US | disclosed |
| EP-1382603-A1 | NITROGENOUS FUSED−RING COMPOUND HAVING PYRAZOLYL GROUP AS SUBSTITUENT AND MEDICINAL COMPOSITION THEREOF | Eisai Co., Ltd. (JP) | 2004-01-21 | — | — | EP | disclosed |