Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.54 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4467591 | 0.74 | — | — | |
| SCHEMBL2452605 | 0.74 | DAO (0.31) | — | |
| SCHEMBL4460967 | 0.74 | F11 (0.31) | — | |
| SCHEMBL445877 | 0.74 | CYP2A6 (0.48) | CYP2A6KEAP1 | |
| SCHEMBL1202420 | 0.71 | FLT3 (0.42) | — | |
| SCHEMBL37667 | 0.70 | AOC3 (1.00) | AOC3EHMT2CYP2A6 | |
| SCHEMBL29363162 | 0.70 | AOC3 (1.00) | AOC3EHMT2CYP2A6 | |
| SCHEMBL8205395 | 0.69 | CYP2A6 (0.58) | CYP2A6 | |
| SCHEMBL1465757 | 0.69 | SYK (0.32) | — | |
| SCHEMBL2562389 | 0.69 | RHEB (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216230-B1 | FUSED CYCLOHEPTANE AND FUSED AZACYCLOHEPTANE COMPOUNDS AND THEIR USE AS INTEGRIN RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2008-04-23 | — | — | EP | disclosed |