Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 20/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4051561 | 0.85 | ADORA2B (0.67) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL4236079 | 0.83 | ADORA2B (0.54) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL4232452 | 0.77 | ADORA2B (0.56) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL4230739 | 0.73 | ADORA2B (0.54) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL6508766 | 0.71 | ADORA2B (1.00) | ADORA2BADORA2AADORA1 | |
| SCHEMBL4063346 | 0.70 | ADORA2B (0.63) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL4049709 | 0.69 | ADORA2B (0.69) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL4054717 | 0.69 | ADORA2B (1.00) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL4055276 | 0.69 | ADORA2B (0.71) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL4057916 | 0.68 | ADORA2B (0.73) | ADORA2BADORA2AADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492793-B1 | NEW-4-(PYRROLOPYRIMIDIN-6-YL)BENZENESULPHONAMIDE DERIVATIVES | ALMIRALL LAB (ES) | 2008-01-16 | — | — | EP | disclosed |