Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyric Acid SCHEMBL4161192 | 0.89 | ROCK2 (0.33) | ROCK2AURKATPX2 | |
| SCHEMBL4713961 | 0.83 | PARG (0.38) | ROCK2ROCK1 | |
| SCHEMBL3253927 | 0.79 | CSNK2A2 (0.33) | — | |
| SCHEMBL3253930 | 0.79 | CSNK2A2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL3250727 | 0.79 | CSNK2A2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL3250722 | 0.79 | CSNK2A2 (0.32) | — | |
| SCHEMBL4717883 | 0.76 | GRIN2D (0.37) | — | |
| Hydrochloric Acid SCHEMBL4161189 | 0.74 | GPR17 (0.32) | — | |
| Butyric Acid SCHEMBL4167771 | 0.73 | BRAF (0.33) | ROCK2 | |
| Butyric Acid SCHEMBL4166107 | 0.73 | BRAF (0.33) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899335-A1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PIERRE FABRE MEDICAMENT (FR) | 2008-03-19 | — | — | EP | claimed |
| WO-2007003611-A1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PIERRE FABRE MEDICAMENT (FR) | 2007-01-11 | — | — | WO | claimed |