Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | TGM2 | P21980 | 11/20 | 0.55 |
| ▸ | F13A1 | P00488 | 9/20 | 0.55 |
| ▸ | TGM1 | P22735 | 6/20 | 0.55 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL392870 | 0.83 | KMT2A (0.64) | MEN1KMT2ATGM2F13A1TGM1 | |
| SCHEMBL2826209 | 0.82 | TDP1 (0.64) | MEN1KMT2ALMNAALDH1A1TGM2 | |
| SCHEMBL19683494 | 0.80 | KMT2A (0.74) | MEN1KMT2ALMNAALDH1A1TDP1 | |
| SCHEMBL29060789 | 0.80 | MAPT (0.73) | MEN1KMT2AALDH1A1TGM2F13A1 | |
| SCHEMBL4760580 | 0.79 | MEN1 (0.97) | MEN1KMT2ALMNAALDH1A1TDP1 | |
| SCHEMBL4761472 | 0.79 | MEN1 (0.91) | MEN1KMT2ALMNAALDH1A1TDP1 | |
| SCHEMBL22405787 | 0.78 | TGM2 (0.64) | MEN1KMT2ALMNAALDH1A1TGM2 | |
| SCHEMBL4716208 | 0.77 | MEN1 (1.00) | MEN1KMT2ALMNAALDH1A1TDP1 | |
| SCHEMBL4716285 | 0.77 | MEN1 (1.00) | MEN1KMT2ALMNAALDH1A1TDP1 | |
| SCHEMBL4274049 | 0.77 | STS (0.60) | TGM2F13A1TGM1TGM3CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615904-B1 | SUBSTITUTED BENZOSULPHONAMIDES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ASTRAZENECA AB (SE) | 2008-02-27 | — | — | EP | disclosed |
| US-20070021606-A1 | Therapeutic compounds | ASTRAZENECA AB (SE) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021606-A1 | Therapeutic compounds | GRIN1, GRIN3A, GRM2 | MEN1 4633/4885KMT2A 3726/4885LMNA 4722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.