Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4025655 | 0.89 | TSHR (0.40) | KMT2ATSHRHTTSMN1; SMN2MEN1 | |
| SCHEMBL4713476 | 0.88 | KMT2A (0.39) | KMT2ATSHRHTTSMN1; SMN2MEN1 | |
| SCHEMBL4711906 | 0.87 | EPHX1 (0.38) | ALDH1A1NPSR1PPARGMAPTLMNA | |
| SCHEMBL4021417 | 0.83 | LIMK2 (0.39) | KMT2ATSHRHTTSMN1; SMN2MEN1 | |
| SCHEMBL4025652 | 0.82 | HTT (0.39) | KMT2ATSHRHTTSMN1; SMN2MEN1 | |
| SCHEMBL4711947 | 0.78 | TSHR (0.41) | KMT2ATSHRHTTSMN1; SMN2MEN1 | |
| SCHEMBL5047519 | 0.76 | CASR (0.39) | KMT2ATSHRHTTSMN1; SMN2MEN1 | |
| SCHEMBL4711910 | 0.74 | MAPT (0.40) | MAPTLMNAPOLB | |
| SCHEMBL4716454 | 0.73 | TSHR (0.43) | KMT2ATSHRHTTSMN1; SMN2MEN1 | |
| SCHEMBL4714622 | 0.73 | TSHR (0.56) | KMT2ATSHRHTTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986637-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | Laboratoires Serono SA (CH) | 2008-11-05 | — | — | EP | claimed |
| WO-2007093557-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | LABORATOIRES SERONO S.A. (CH) | 2007-08-23 | — | — | WO | claimed |