SCHEMBL4718692

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4716052	0.98	PDE4B (0.51)	TRPV1PDE4BMAPTTP53CYP1A2
	SCHEMBL4718504	0.89	TRPV1 (0.59)	TRPV1PDE4BMAPTTP53ALDH1A1
	SCHEMBL4716401	0.89	TRPV1 (0.48)	TRPV1PDE4BMAPTTP53ALDH1A1
	SCHEMBL4719637	0.89	TRPV1 (0.48)	TRPV1PDE4BMAPTCYP1A2CYP3A4
	SCHEMBL4716096	0.86	TRPV1 (0.46)	TRPV1PDE4BCYP1A2CYP3A4CLK4
	SCHEMBL4718513	0.86	ALDH1A1 (0.53)	TRPV1PDE4BMAPTTP53CYP1A2
	SCHEMBL4715609	0.86	ACP1 (0.52)	TRPV1MAPTTP53CYP1A2CYP3A4
	SCHEMBL4716832	0.86	TRPV1 (0.67)	TRPV1ABL1BCR
	SCHEMBL4717175	0.86	ALDH1A1 (0.50)	TRPV1PDE4BMAPTTP53CYP1A2
	SCHEMBL4718637	0.86	TRPV1 (0.55)	TRPV1ABL1BCRCCR4KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.