Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 16/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721450 | 0.87 | CCR8 (0.53) | CCR8ALOX5KCNH2HTR1AADRA1D | |
| SCHEMBL3923700 | 0.80 | CCR8 (0.69) | CCR8KCNH2 | |
| SCHEMBL4721447 | 0.69 | CCR8 (0.74) | CCR8KCNH2HTR1AADRA1DADRA1A | |
| SCHEMBL3919797 | 0.69 | CCR8 (1.00) | CCR8KCNH2 | |
| SCHEMBL3919790 | 0.69 | CCR8 (1.00) | CCR8KCNH2 | |
| SCHEMBL4716097 | 0.69 | CCR8 (0.49) | CCR8KCNH2 | |
| SCHEMBL4716924 | 0.68 | CCR8 (0.53) | CCR8KCNH2HTR1AADRA1DADRA1A | |
| SCHEMBL3930004 | 0.67 | CCR8 (0.65) | CCR8KCNH2 | |
| SCHEMBL3929996 | 0.67 | CCR8 (0.65) | CCR8KCNH2 | |
| SCHEMBL3922143 | 0.64 | CCR8 (0.62) | CCR8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567520-B1 | QUINOLINES AND NITROGENATED DERIVATIVES THEREOF AND THEIR USE AS ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2008-10-15 | — | — | EP | claimed |