Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4719100 | 0.82 | NPSR1 (0.45) | NPSR1GAAALDH1A1HTTKDM4E | |
| SCHEMBL4722946 | 0.81 | NPSR1 (0.57) | NPSR1GAAALDH1A1HTTKDM4E | |
| SCHEMBL4723396 | 0.80 | NPSR1 (0.51) | NPSR1GAAALDH1A1HTTKDM4E | |
| SCHEMBL4720608 | 0.70 | NPSR1 (0.56) | NPSR1GAAALDH1A1HTTKDM4E | |
| SCHEMBL4722026 | 0.69 | NPSR1 (0.57) | NPSR1GAAALDH1A1HTTKDM4E | |
| SCHEMBL4721749 | 0.69 | NPSR1 (0.65) | NPSR1GAAALDH1A1HTTKDM4E | |
| SCHEMBL4722259 | 0.69 | NPSR1 (0.57) | NPSR1GAAALDH1A1HTTKDM4E | |
| SCHEMBL14101807 | 0.69 | NPSR1 (0.57) | NPSR1GAAALDH1A1HTTKDM4E | |
| SCHEMBL4721661 | 0.67 | MAPT (0.71) | NPSR1GAAALDH1A1HTTKDM4E | |
| SCHEMBL15772429 | 0.66 | MCHR1 (0.46) | NPSR1GAAALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |