Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722946 | 0.87 | NPSR1 (0.57) | NPSR1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL4719100 | 0.81 | NPSR1 (0.45) | NPSR1MAPTGAAALDH1A1HTT | |
| SCHEMBL4718801 | 0.80 | NPSR1 (0.46) | NPSR1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL14101721 | 0.78 | NPSR1 (0.51) | NPSR1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL4721647 | 0.76 | MAPT (0.76) | NPSR1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL4721749 | 0.73 | NPSR1 (0.65) | NPSR1MAPTMEN1KMT2AGAA | |
| SCHEMBL14101807 | 0.73 | NPSR1 (0.57) | NPSR1MAPTMEN1KMT2AGAA | |
| SCHEMBL4722026 | 0.73 | NPSR1 (0.57) | NPSR1MAPTGAAALDH1A1HTT | |
| SCHEMBL4722259 | 0.73 | NPSR1 (0.57) | NPSR1MAPTMEN1KMT2AGAA | |
| SCHEMBL4720608 | 0.72 | NPSR1 (0.56) | NPSR1MAPTGAAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |