Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 17/20 | 0.60 |
| ▸ | PTGDR | Q13258 | 6/20 | 0.54 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3085501 | 0.85 | PTGDR2 (0.70) | PTGDR2PTGDRPTGER2CYP2C9BAZ2B | |
| SCHEMBL4721545 | 0.80 | BAZ2B (0.64) | PTGDR2PTGDRPTGER2BAZ2BHDAC1 | |
| SCHEMBL4722882 | 0.80 | BAZ2B (0.53) | PTGDR2PTGDRPTGER2CYP2C9BAZ2B | |
| SCHEMBL4719430 | 0.77 | PTGDR2 (0.59) | PTGDR2PTGDRCYP2C9BAZ2BHDAC1 | |
| SCHEMBL4721439 | 0.77 | PTGDR2 (0.59) | PTGDR2PTGDRPTGER2CYP2C9BAZ2B | |
| SCHEMBL4719539 | 0.77 | PTGDR2 (0.58) | PTGDR2PTGDRPTGER2CYP2C9BAZ2B | |
| SCHEMBL4720175 | 0.77 | KRAS (0.51) | PTGDR2BAZ2BHDAC1HDAC6 | |
| SCHEMBL3094291 | 0.75 | PTGDR2 (1.00) | PTGDR2PTGDRPTGER2CYP2C9 | |
| SCHEMBL3085707 | 0.72 | PTGDR2 (0.81) | PTGDR2PTGDRPTGER2CYP2C9 | |
| Hydrochloric Acid SCHEMBL3084889 | 0.71 | PTGDR2 (0.58) | PTGDR2PTGDRPTGER2HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725553-B1 | TETRAHYDROPYRIDOINDOLE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-05-07 | — | — | EP | claimed |